The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease, and Inheritance

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Columbia University Press, Feb 14, 2012 - Science - 352 pages
Epigenetics has the potential to revolutionize our understanding of the structure and behavior of biological life on earth. It explains why mapping an organism’s DNA code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Conducting a survey of the twenty-year history of the field while also showcasing its latest findings, this volume provides a solid introduction for grasping the foundations of epigenetics, the field’s recent discoveries and innovations, and its practical and theoretical applications. Epigenetics is now informing work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma.

A leading epigenetics researcher, Nessa Carey also connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies, why tortoiseshell cats are always female, why some plants need cold weather before they can flower, and how we age and develop disease. She concludes with future directions for research and the ability for epigenetics to improve human health and well-being. Published in the United Kingdom in 2011 and widely praised on both sides of the Atlantic, this new book is sure to become a classic in modern biology.
 

Contents

Introduction
1
An Ugly Toad and an Elegant Man
11
How We Learned to Roll Uphill
23
Life As We Knew It
42
Life As We Know It Now
54
Why Arent Identical Twins Actually Identical?
75
The Sins of the Fathers
97
The Generations Game
115
Fighting the Enemy Within
205
All in the Mind
233
The Downhill Slope
262
Long Live the Queen
282
The Green Revolution
293
The Ways Ahead
304
Notes
313
Glossary
325

The Battle of the Sexes
129
Generation X
152
The Message is Not the Medium
178

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About the author (2012)

Nessa Carey is a visiting professor at Imperial College in London and currently works in the biotechnology and pharmaceutical industries, where she has specialized in epigenetics for nearly a decade. She has strong relationships with leading epigenetics researchers, medical labs in Europe, and with some of the most prestigious institutions in the United States, including the Harvard Medical School, the MD Anderson Cancer Center, and the Wistar Institute.

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