A Guide to the Extrapyramidal Side Effects of Antipsychotic DrugsAntipsychotic drugs have revolutionised the management of major psychiatric disorders and the outcomes of those who suffer from them. They are, however, possessed of a range of adverse effects, amongst the most frequent and distressing of which are those resulting in disturbance of voluntary motor function. Extrapyramidal side effects - or E.P.S. - are still poorly recognised and not infrequently misattributed. Despite a vast research literature, there have been few attempts to bring together both the descriptive clinical elements of these disorders and major research conclusions pertinent to routine practice. This very readable and well illustrated 1999 book seeks to rectify this in the hope of increasing clinicians' awareness of the issues and acknowledgement of their impact. This is a task made more rather than less urgent with the emergence of drugs of lower liability but which may promote subtler abnormality than standard compounds. |
Contents
Acute dystonias | 33 |
Parkinsonism | 89 |
Akathisia | 130 |
Tardive dyskinesia | 166 |
Tardive and chronic dystonia | 227 |
Special populations | 251 |
The clinical examination | 265 |
An overview of some standardised recording | 284 |
Some medicolegal and qualityofcare issues | 306 |
References | 320 |
| 346 | |
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A Guide to the Extrapyramidal Side Effects of Antipsychotic Drugs D. G. Cunningham Owens Limited preview - 1999 |
Common terms and phrases
abnormality acute akathisia acute dystonias adverse effects akathisia anti anticholinergics antidopaminergic antipsychotic drugs assessment associated behaviours benzodiazepines blepharospasm body bradykinesia cent chlorpromazine choreiform chronic dystonia clinical clinicians clozapine complex compounds comprising context diagnosis disability dopamine dopaminergic dose drug-related parkinsonism dystonic early elderly emerge emphasised especially evaluation evidence examination exposure extrapyramidal extrapyramidal disorders fact factors fluphenazine Furthermore haloperidol hyperkinetic disorders idiopathic impairment increasing involuntary movements issue Journal of Psychiatry L-dopa limbs literature long-term major medication ment mental mild motor disorders movement disorders muscles neuroleptic neuroleptic-induced neurological Nonetheless noted onset orofacial Parkinson's disease pathophysiology patients pharmacological population postural practice predisposing present prevalence problem Procyclidine propranolol Psychopharmacology psychotic rating scales receptor regimes relation relationship reported restlessness risk risperidone Sachdev sample schizophrenia seen signs specific standardised studies symptomatology symptoms syndrome Table tardive akathisia tardive dyskinesia tardive dystonia Tetrabenazine therapeutic tion treatment tremor
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