Toxic Substances in Crop Plants
J. P. Felix D'Mello, C. M. Duffus, John H. Duffus
Woodhead Publishing, 1991 - Science - 339 pages
This volume reviews current knowledge of toxic substances in crop plants with particular reference to their anti-nutritional effects in animals and man and the potential for detoxification. The distribution and ecological significance of these compounds is also addressed. Continuing disquiet over the use of animal by-products in livestock nutrition has provided renewed impetus for the greater exploitation of conventional and novel crop plants both as food and as industrial raw materials. However, a major factor restricting the utilisation of such crops in animal nutrition is the presence of a diverse array of toxic substances capable of inducing effects ranging from loss of hair and wool to severe neurological disorders and even death. Significant advances have been made to establish the nature of these compounds and to assess their effects in animals and man. As in other branches of biomedical research, these developments have been achieved through the multidisciplinary efforts of chemists, biochemists, toxicologists, nutritionists and molecular geneticists. This volume reviews current knowledge of toxic substances in crop plants with particular reference to their anti-nutritional effects in animals and man and the potential for detoxification. The distribution and ecological significance of these compounds is also addressed.
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absorption Academic Press activity aflatoxins aglycone alfalfa alkaloids amino acids animals anti-nutritional antibodies antigens arginine assay bile acids Biochem Biol biosynthesis canavanine cereals chemical cholesterol chymotrypsin Clin coeliac disease colon complex compounds concentrations condensed tannins containing cultivars cyanide cyanogenic dietary fibre diets digestive disease effects enzymes excretion extracts factors feeding Food Agric Food Chem G. R. Fenwick glucosinolate glycoalkaloids glycosides glycyrrhizin growth human hydrolysis I. E. Liener inactivation increased ingestion inhibition intake interaction isoinhibitors isolated J. P. F. D'Mello kidney bean lectins legume levels liver maize meal metabolism metabolites methods mimosine mycotoxins nitrile nitrogen Nutr nutritional occur pancreatic Pharmacol plasma polysaccharides potato protein proteinases Pusztai quinolizidine rats reactive recent reduced residues result rumen ruminants saponin content saponins significant small intestine soyabean soyasaponins species structure studies synthesis tannins tissues toxic Toxicol toxin trichothecenes trypsin inhibitor vitro weight zearalenone