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MAIDEN's case of penetrating wound of the the spermatic artery in sarcocele, ii.
chest, i. 440.

811.
MAINGAULT's mode of amputating at the MAUNSELL'S, Dr., description of noma, i.

knee with the flap cut, ii. 943; mode of 62; on the suppuration of mumps, i. 149;
operating in partial amputation of the on the communication of syphilis to the
foot, ii. 948.

fætus in the womb, i. 673 ; on the symp-
MALAGODI's case of excision of a portion of toms of syphilis in infants, i. 673; on its

the ischiatic nerve in the region of the treatment, i. 674.
knee-joint, ii. 887.

MAURICEAU on the operation for the treat-
MALGAIGNE on the local treatment of frac- ment of lacerated perineum, i. 611 ; on

tured ribs, i. 547; on the frequency of the application of the sutures, i. 611.
dislocation in the different joints, i. 764; Maxillary sinus, disease of, ii. 739; bone,
on the primitive direction of dislocation lower, fracture of, i. 528 ; excision of, ii.
of the humerus, i. 782; case of reduction 986; upper, resection of, ii. 994 ; fracture
of an old dislocation of the elbow, i. 790; of, i. 527; artery, external, ligature of,
on the cause of the difficulty experienced ii. 239.
in reducing the dislocation of the thumb Mayo describes the occasional occurrence of
from the metacarpal bone, i. 795; on the pus-globules in healthy blood, i. 41; case
seat of strangulation in ruptures, ii. 11; of injury to the ligaments of the knee, i.

case of resection of the fibula, ii. 1007. 206 ; describes three distinct forms of
Mammary, internal, ligature of, ii. 249. ulceration of joint-cartilages, i. 228 ; case
MANDT on the chemical and microscopic cha of injury to the ancle, followed by absorp-

racters of pus, i, 35 ; on the pus-globules, tion of the cartilages, and effusion and
i. 40 ; on the presence of globules in the organization of lymph between the ends
serum, i. 43.

of the bones, i. 246; on the progress of
MANEC on the introduction of a piece of caries, i. 682; on inflammation as the

bougie into an ossified artery after ampu cause of caries, i. 684; on the treatment
tation, i. 304; on ligature of the inno. of caries, i. 686; on the application of
minata, ii. 247; mode of amputating at caustic in varix, ii. 292; on hæmatocele,
the hip-joiut by the flap-cut with a single ii. 445 ; on dropsy of the bursæ mucosa,
flap, ii. 937.

ii. 458; on the formation of bursæ from
Manovy's case of division of the posterior pressure, ii. 458; case of large calculus,
tibial nerve, ii. 887.

ii. 546; on tumours of nerves in stumps,
MARCET, Dr., on the premonitory pains of ü, 765.

hydrophobia, i. 371; case of knife-swal- MAYOR's treatment of fractured clavicle, i.
lowing, ii. 398.

551; treatment of false joints, i, 590; on
MARCHETTI's case of swine's tail in the rec- the sutures in the operation for hare-lip, i.
tum, ii. 393.

598; operation for the radical cure of
MARJOLIN on excision of the prolapsed and hernia, ii. 26 ; on extirpation of broncho-
scirrhous womb, ii. 115.

cele by ligature, ii. 664; on ligature of
MAROCHETTI on the presence of pustules the neck of the womb, ii. 822; on ampu-

under the tongue after the bite of a mad tation of the phalanges with the tachy-
animal, i. 375; plan of treatment pro tome, ii. 931.
phylactic of hydrophobia, i. 375; views MEAD, Dr., on viper's fat as a local remedy
objected to by Watson. i. 376.

in viper's bite, i. 354; case of the bite of
MARSHALL on the application of flour in a rattlesnake, i. 354; experiments on
cases of burns, i. 116.

viper-poison, i. 355; on the protraction
Martin on the causes of club-foot, ii. 176. of the period of incubation in hydro-
MARTINEAU's cases of very small urinary phobia, i. 366 ; on the increase of muscu-

calculi, ii. 547; operation for stone in the jar strength in hydrophobia, i. 370
bladder, ii. 587.

MECKEL on the vessels of cartilage, i. 226;
MARTINIÈRE's, DE LA, case of a foreign body on the three kinds of union of divided
in the windpipe, ii. 395.

parts-quick union, by adhesion, and by
MAUCHART on incision and scarifications of granulation, i. 288; on the causes of cere-

the hernial sac, for its radical cure, ii. 24. bral rupture, ii. 99; case of cure of cere-
MAUNOIR on the effects produced by the bral rupture, ii. 99; on the influence of

ligature on the arterial coats, ii. 219; on spinal curvature on the transverse djame.
the ligature of the spermatic artery in va ter of the pelvis. ii. 158 ; on the division
ricocele, ii. 297 ; treatment of bronchocele of tumours, ii. 648; opinion that melano-
by puncture and irritating injections, and sis is the same as medullary fungus, ii.
by seton, ii, 663; on simple serous cysts 723.
of the neck, ii. 695 ; on the chemical con- MEDIN on the stanching the bleeding from
stituents of the brain-like substance in an intercostal artery, i. 448.
medullary fungus, ii. 719; on ligature of MEDING's experiments on incomplete frac-
ture, i. 497 ; on the production of callus, MERCIER's opinions on the changes which
i. 501.

the substance of the bone undergoes in
MEDULLARY FUNGUS, ii. 715; characters, advanced age, i. 497 ; on inversion of the

ii. 715; symptoms and situation, ii. 717; foot in fracture of the neck of the femur,
medullary fungus of the testicle, ii. 717; i. 565; on the characters of horns, ii.
symptoms and termination, ii. 717 ; of 671; on the treatment to be adopted when
medullary fungus of bone, ii. 718; Astley air enters a vein during an operation, ii.
Cooper on medullary fungus of bone, ii. 856.
718; appearances of the parts on dis- Mercurial disease, i. 675.
section, ii. 718; chemical examination MERREM, Dr., on wounds of the uterus, as
of the brainlike substance, ii. 719; Hecht, predisposing to rupture in subsequent la-
Maupoir, and Müller on the chemical bours, i. 484; explanation of this fact, i.
constituents of the brain-like substance, 484.
ii. 719; Krause on the microscopic cha- Méry on incision of the hernial sac and the
racters of medullary fungus, ii. 719; introduction of lint tents for its radical
Glage on the nature of, ii. 719; me- cure, ii. 24.
dullary fungus occasionally encysted, ii. Mesenteric and mesocolic ruptures, ii. 93.
720; characters of the brain-like sub Metacarpal bones, amputation through, ii,
stance in medullary fungus of the testicle, 927 ; exarticulation of, at the carpus, ii.
ii. 720; characters of medullary fungus, 963; excision of, ii. 965.
ii. 721; Allan Burns and von Walther on Metacarpus, excision of the joints of, ii. 985.
the difference between fungus hæmatodes Metastatic abscesses, i. 36.
and sarcoma medullare, ii. 721 ; Aber Metatarsal bones, amputation through, ii.
nethy on fungus hæmatodes, ii. 721; 927; exarticulation of, ii. 949; excision
Möller on the applicability of the term of, ii. 966; fracture of the bones of, i. 562.
"medullary fungus" to the different forms Metatarsus, excision of the joints of, ii. 985.
of soft cancer, ii. 722; Vogel on the METTAUER, Dr., on the operation of staphy-
essential element of medullary fungus, ii. loplasty by granulation, i. 600.
722; Bradley, Jaeger, and Vogel on the MEYER on the application of nitric acid to
blood fungus, ii. 722; Meckel's opinion the scar of nerves, i. 330; apparatus for
that melanosis is the same as medullary fracture of the neck of the femur, i. 569;
fungus, ii. 723; this opinion only partially case of strictured csophagus communi-
correct, ii. 723; diagnosis between me cating with the left bronchus, ii. 320;
dullary fungus and scirrhus, ii. 724; case of resection of the clavicle, ii. 1003.
Breschet's different kinds of carcinoma, MICHAELIS on the treatment of gonorrhea,
merely different degrees of development i. 175; on the operation for the ingrowing
of medullary fungus, ii. 725; Abernethy's of the nail, i. 200 ; on the division of the
sarcoma tuberculatum considered by tendo Achillis in club-foot, ii. 182; on
Meekel to be medullary fungus, ii. 725; the doubtful character of the old cases in
this opinion incorrect, ii. 725; etiology which the Cæsarian operation is reported
of medallary fungus, ii. 725; diathesis to have been performed several times
fungosa, ii. 725 ; seat and mode of forma successfully on the same woman, ii, 438;
tion of medullary fungus, ii. 725; treat case in which the operation was per-
ment of the disease almost entirely inef formed four times on the same woman,
fective, ii. 726 ; early ablation of the part ii. 439; on the danger attending the effu-
or amputation of the limb affords the sion of the secretions from the wound
only chance of cure, ii. 726; the disease into the belly, ii. 442; on the exhibition

generally returns sooner or later, ii, 726. of opium, and on the necessity of keeping,
MEIG's plan of treatment in ingrowing of the bowels open after the operation, ii.

the nail by a compress and linen-roller, i. 442; on the greater probability of success
200.

attending the repetition of the operation,
MELIER'S apparatus for dislocation of the than in the first instance, ii. 444.
clavicle forwards, i. 779.

MIESCHER on the ossification of arteries, i.
MELKER'S diagnostic sign for vertebral 77 ; says no difference between permanent
caries, i. 281.

cartilage, and that which is to be con-
MELLE's case of dislocation of the scapular verted into bone, i, 223; differs in opinion

end of the clavicle downwards, i. 780. with W. Hunter respecting the fibrous
MENDAGA on the hydrarg. cyan. in syphilis, structure of articular cartilage, i. 223 ;
i. 662.

on the production of callus, i. 501 ; sum-
MENDE On the seeming retroversion of the mary of views on the formation of the

womb at the latter periods of pregnancy, primary and secondary callus, i. 501 ;
ii. 140.

experiments to induce suppuration in
MEXZEL on the operation for the treatment compound fractures, i. 510; summary of
of lacerated perineum, i. 611.

experiments to ascertain the processes"
VOL. I.

under which suppurating fractures are of pus, i. 35, on the reduction of the dis-
united, i. 516 ; on the granulations attend located femur by placing the foot between
ing caries, i. 682 ; on the characters of the thighs, and making extension and
caries, i. 683; on the seat of the various rotation, i. 801 ; case of a pouch formed
kinds of caries, i. 684; on the signs of at the mouth of the tunica vaginalis,
exfoliation, i. 692; on the absorption of ii. 4.
part of the dead bone in the process of MORRIS', Dr., case of injurious effects pro-
exfoliation, i. 692; on the process of cica- duced by the inhalation of ether, ii.
trization after necrosis, i. 695.

1008.
MIRAULT's operation for the ligature of the MORTIFICATION :- divided by Chelius into
tongue, ii. 779.

the hot and cold, i. 53; Travers' objection
Möbus' case of vertebral aneurism, ii. 250. to the terms mortification and sphacelus,
MODEL's opinion that spurred rye does not i. 53; definition of mortification, i. 53;

cause gangrene in beasts, i. 61; disproved symptoms, i. 54; Travers' acute gangrene,
by Tessier, i. 61; Block's experiments on i. 54; destruction of the mortified parts
the subject, i. 61.

occurs either as dry, moist, or hospital
MOHRENHEIM's apparatus for fracture of gangrene, i, 54 ; South on vesications
the patella, i. 579.

filled with a bluish or bluish-black fluid
Moj'sisovio's equilibrium plan in fracture in cases of severe bruise, or when the
of the femur, i. 574.

bandages in cases of fracture are too
MÖLLER's case of gangrene of the penis, tight, i. 55; causes of mortification, i. 55;

from the constriction of a metal ring, i. Brodie on sudden loss of blood, a cause
487.

of mortification, i. 55; Travers on deep
MONNIER'S, LE, operation of staphyloraphy, and extensive effusion, and on injuries
i. 603.

of nerves, as causes of mortification, i.
MONRO on the lengthening of the limb in 55 ; South's case of mortification of the

hip-disease, i. 257; slippers for rupture lower extremity from effusion of blood
of the tendo Achillis, i. 494 ; on the appli causing distension of the limb, i. 55;
cation of caustic for the radical cure of mortification in cases of aneurism caused
hernia, ii. 24; on the dilatation of the by distension from effusion, i. 56; mor-
abdominal ring, the hernial sac being tification in cases of simple fracture, the
unopened, ii. 43; cases of half-pence in principal artery of the limb being un-
the cesophagus, ii. 382; case of a foreign injured, i. 56; South's cases of mor-
body in a sac behind the esophagus at tification after fever, i. 56; senile gan-
its origin, ii. 382.

grene, i. 57; distinction between senile
Montain on the operation for the treatment gangrene consequent on injury, and that

of lacerated perineum, i. 611; on the resulting from constitutional causes, i. 57;
application of the sutures, i. 611.

Travers chronic gangrene, i. 58; causes
MONTEIRO's case of ligature of the aorta, of dry gangrene, i. 59; South's case of
ii. 255.

dry gangrene consequent on abdominal
MONTGOMERY, Dr., on the origin of scirrhus typhus, i. 59; Dupuytren on arteritis, a

uteri in the ova Nabothi, ii. 817; case of cause of dry gangrene, i. 59, 75; South's
cancer uteri, ii. 818.

case of dry gangrene from organic disease
MORAND on the arrest of hæmorrhage by of the heart, i. 59; Brodie's case of dry

nature, i. 297 ; on the extirpation of the gangrene from inflammation of the prin-
ovary, ii. 487; mode of amputating at the cipal artery and vein of a limb, i. 59;
shoulder-joint with the circular cut, ii. Brodie on the cause of the distinction
958.

between dry and moist gangrene, i. 59;
MOREAU's case of excision of a joint, ii. 969;

gangrene from arterial inflammation a
on the excision of joints, ii. 969; statistics comparatively rare disease, i. 59; this
of cases, ii. 970; mode of operating in statement denied by Cruveilbier and
excision of the head of the humerus, ii. Dupuytren, i. 59; South's case of arteritis
974; in excision of the elbow-joint, ii. without gangrene, i. 60; Solly's case of
975 ; on the division of the ulnar nerve

gangrene, i. 60; mortification from con-
in excision of the elbow-joint, ii. 975; tinued pressure, i. 60; mortification from
mode of operating in excision of the knee the use of the cock-spurred rye, i, 60;
joint, ii. 981; on the mode of union after Thomson's account of this form of the
the operation, ii. 982; mode of operating disease, i. 61; Sigebert and Bayle's re-

in excision of the ancle-joint, ii, 983. marks, i. 61; the disease first noticed by
MORÈRE's case of abscess of the womb, i. Dodard, afterwards by Saviard, Noel,
484.

Langius, Quassoud, Bossau, and Duha-
MORGAGNI on the causes of varicocele, ii. mel, i. 61; Elliotson's case of gangrene
296.

of the leg after the use of ergot, the arte-
MORGAN's opinions relative to the formation ries of the limb being also ossified, i. 61;
Model's opinion that spurred rye does not by scarifications in the gangrenous parts,
cause gangrene in beasts. i. 6); disproved i. 95; these latter must not penetrate into
by Tessier, i. 61; Block's experiments on the living parts, i. 95; scarifications are
the subject, i. 61; Dr. C. Woolaston's dangerous in gangrena senilis, i. 95 ;
cases of gangrene, i. 61; mortification of amputation not applicable in gangrene
the cheek, called noma by Vogel, i. 61; depending on an internal cause still in
a rare and generally fatal disease, i. 61; operation, i. 95; applicable after the line
description of doma by Drs. Evanson and of demarcation has formed, or in gan-
Maunsell, i. 62; the term, cancrum oris, grene from external violence, even while
incorrectly applied to noma, i. 62; can still proceeding, i. 95; South's opinion
crum oris, a form of mortification com that amputation should never be per-
mencing with ulceration, generally first formed while the gangrene is in progress,
in the gums, and thence spreading to the i. 95; treatment of senile gangrene, i. 96;
lips and cheeks, i. 62; described by Dr. when resulting from an injury, soothing
Camming, i. 62 ; South's case of noma in or dry aromatic applications, or leeching,
the adult, i. 62; mortification, a conse if the inflammation be active, i. 96 ;
quence of contagious influence, results in Dupuytren employed the antiphlogistic
malignant pastule, or hospital gangrene, plan of treatment in plethoric subjects,
i. 63; malignant pustule, its causes and i. 96; when from constitutional causes,
symptoms, i. 63; contagious from beasts tonics and opium necessary, i. 96; treat-
to man, but not from man to man, i. 63 ; ment of gangrene from pressure, i. 96;
Elliotson on glanders in the human sub from the use of spurred rye, i. 96; Thom-
ject, i. 64; Lawrence's cases of malignant son and S. Cooper's cases, i. 97; treatment
postule, i. 64; Beer's and Delpech's cases, of malignant pustule, i. 97 ; local treat-
i. 65; Turchetti's cases of malignant pus ment by cutting out the pustule, and
tule, described by him as anthrax, i. 66; cauterizing the wound, i. 97; if the pus-
Dr. Wagner's cases of malignant pustule, tule not deep, but the slough much spread,
produced by contact, and by eating the deep scarifications and the application of
ilesh of diseased animals, i. 66; Dr. caustic recommended, i. 97; employment
Bourgeois' observations on malignant pus of constitutional treatment, i 97; treat-
tule, i. 67 ; hospital gangrene, i. 68 ; de ment of hospital gangrene. i. 97: emetics
scription of the disease, i. 68; local and advised by Pouteau and Dussausoy, i. 97;
general symptoms, i. 68; Liston's account washing the sore with vinegar or solution
of the hospital gangrene in University of arsenic in the commencement of the
College Hospital in 1841, i. 68; Arnott's disease, i. 97; the entire surface to be
cases of hospital gangrene at the Middle touched with nitrate of silver, i. 98; the
sex Hospital, i. 69; the disease exceed free application of the actual cautery
ingly rare in the London hospitals, i. 69 ; most effectual, i. 98; constitutional treat-
Lawrence on sloughing phagedena, i. 69; ment should be employed at the same
Welbank on sloughing phagedena, i. 70; time, i. 98; gangrenous destruction of
this disease regarded by S. Cooper as parts from burns, i. 110; treatment of
resembling hospital gangrene, i. 70; de mortification caused by burns, i. 112;
nied by South, i. 70; South on the slough cold wet sufficient to induce mortifi-
ing state of stumps from want of power, cation, if continued sufficiently long to
i. 70; the characteristic of hospital gan reduce the natural heat below a certain
grene, i. 70; the cause of hospital gan standard, i. 126; gangrene the result of
grene is the operation of a peculiar con too suddenly warming a frozen limb, i.
tagious matter, i. 70; it is always a very 129; treatment of a frozen part in which
dangerous complication of wounds and mortification is threatened, from its hav-
sores, i. 70; treatment of gangrene, i. 94; ing been too hastily warmed, i. 130; when
when connected with active inflammation, mortification has taken place, it must be
and inflammatory fever, moderate anti treated in the usual manner, i. 130; treat-
phlogistic treatment to be employed, i. ment of gangrenous chilblains, i. 131;
94; if caused by the constriction of gangrene of the testicle a rare termina-
wyielding aponeuroses, they must be tion of inflammation, i. 179; causes and
divided, i. 94; when connected with treatment of mortification in compound
general debility, tonics and mineral acids fractures, i. 509; South on mortification
indicated, i. 94 ; local treatment of gan in compound fractures, and its treatment,
grene, i, 94; if there be active inflamma local and general, i, 511; sloughing of
tion, soothing poultices : if the part be the omentum in strangulated hernia, ii.
free from pain, and shrivelled, stimulant 41; gangrene of the intestine in strangu-
applications required, i. 95 : remedies lated hernia, ii. 42.
which prevent the influence of the gan- MORTON on the inhalation of ether prior to
grenous juices, i. 95; their action aided the extraction of teeth, ii. 1007.

Moscati on the extirpation of the tonsils Muscies, lacerations of, i. 494.
· by cutting, i. 145.

MUSSEY's, Dr., case of ligature of both
MOSELY's, Dr., case of scorpion sting, i. 351; ! carotids, ii, 232; on the treatment to be
on the chigoe, i. 352.

adopted when air enters a vein during an
MOTHE on the primitive direction of dislo operation, ii. 856; case of resection of the
cation of the humerus, i. 782.

scapula and clavicle together, ii. 1004.
Mott on the treatment of fistula of the MÜTTER's plastic operations for the relief
· rectal sheath, i, 733; on the operation of deformities from burns, i. 125; on the
· for tying the innominata, ii. 245; opera period at which the operation for hare-lip

tion for the ligature of the common iliac, should be performed, i. 596 ; on the ad-
ii. 256; mode of amputating at the hip vantage of operating early in hare-lip
joint with two flaps, ii. 938; case of ex and cleft-palate, i. 599; on the treatment
cision of part of the side of the lower jaw, of cleft-palate after the operation for hare
without the condyle. ii. 988; mode of lip, i. 599; on the use of obturators in
operating in excision of the lower jaw cleft-palate, i. 600; on the operation of
with the condyles, ii. 989; on the previous staphyloplasty by granulation, i. 600;
ligature of the carotid artery, ii. 990; case successful operation in a case of loss of
of exarticulation of one side of the lower substance in the hard palate from chronic
jaw, ii. 993; case of resection of the mercurial disease, i. 601.
clavicle, ii. 1004.

MYNORS' mode of amputating by the circular
MOTTE, LA, on the operation for the treat incision, ii. 890.

ment of lacerated perineum, i. 611; on

the application of the sutures, i. 611. NAËCELE on the use of the suture in vesico-
MOUFFET on the acarus scabiei, i. 636.

vaginal fistula, i. 753, 755.
Mouth, narrowing and closure of, ii. 315; NAËGELE'S, JUN., case of womb at the eighth
· foreign bodies in the, ii. 380.

month of pregnancy, ruptured by exter-
Moxas, application of, ii. 882,

nal violence, i. 485.
MOZILEWSKY's case of reduction of the con- | NANNONI on amputation at the shoulder-

secutive dislocation in hip-disease, i. 268. joint, with the circular cut, ii. 958.
MÜLDER's mode of operating in excision of Nasal bones, fracture of, i. 526.

the knee-joint, ii. 981; in excision of the NASSE's case of lymph-swelling from exter-
ancle-joint, ii. 983.

nal injury, i. 48; on injecting a solution
MÜLLER on inflammation, i. 22; comparison of neutralized nitrate of mercury into a

of the effects of heat and cold on the body, cold abscess, i. 90.
· i. 126 ; on the vessels of cartilage, i. 227; NAUMBURG on the causes of club-foot, i.

on the causes of necrosis, and on the pro- 176.

cess of regeneration, i. 687; on the pro. NECK, WOUNDS OF THE, i. 431 ; nature of the
• duction of new bone after necrosis, i, 694; wounds, i. 431 ; Astley Cooper on wounds

on the division of tumors, ii, 648; on of the throat, i. 431 ; deep penetrating
enchondron, ii. 674; on the varieties of wounds, with injury of the large vessels, i.
fatty tumors, ii. 691; on the chemical 431; Travers' case of suicidal wound of
constituents of the brain-like substance in the lingual or facial artery near its

medullary fungus, ii. 719; on the appli origin, with unsuccessful ligature of the
·cability of the term “ medullary fungus” common carotid, i. 432 ; injuries of the

to the different forms of soft cancer, ii. pneumo-gastric nerve, i. 432; of the re-
722; on the four several kinds of carci. current nerve, i. 432; of the laryngeal
noma, ii. 757 ; on carcinoma simplex et nerve, i. 432; Dupuy's experiments on
fibrosum, ii. 757 ; on carcinoma reticulare, the division of both pneumogastric nerves,
ii, 757; on carcinoma alveolare, ii. 758; i. 432; injury of the sympathetic or
on carcinoma fasciculatum, ii, 758; pro phrenic nerve, or of the spinal marrow,
posal to separate the fibrous part of the i. 432; wound of the windpipe, i. 432;
blood prior to transfusion, ii. 880.

loss of voice in large wounds of the wind-
MÜNZENTHALER's mode of operating in ex pipe, i. 432; Hennen on emphysema in

articulation of the metatarsal bones, ii. wounds of the windpipe, i. 432; treatment
950.

of transverse wounds of the windpipe, i.
MURRAY'S, Dr., case of ligature of the aorta, 433; Fricke on the treatment of severe
ii. 254.

wounds of the neck, i. 433; South on po-
MURSINNA on the more general application sition in the treatment of wounds of the

of the trephine, i. 413; on the treatment windpipe, i. 433; South on the treatment
of fractures of the neck of the femur, i. of such wounds, i. 433; treatment of the
570; on the operation for the treatment general symptoms accompanying such
of lacerated perineum, i. 611; on the I wounds, i. 433; subsequent treatment, i.
primitive direction of dislocation of the 434; South on the treatment of such
humerus, i. 782.

wounds, when there is much inflamma-

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