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it is perennial, tapering, branched towards the bottom, and contains a milky juice; the stalks are numerous, slender, twining, and spread themselves upon the ground, or neighbouring trees, to the extent of fifteen or twenty feet; the leaves are arrow-shaped, smooth, of a bright green colour, and stand upon long footstalks: the flowers are funnel-shaped, yellowish, plicated, and, according to Dr. Russel, placed in pairs upon the pedicles: the calyx is double, consisting of four emarginated leaflets in each row: the capsule is three and sometimes four locular, containing seeds of a pyramidical shape. No part of the dried plant possesses any medicinal quality but the root, which Dr. Russel administered in decoction, and found it to be a pleasant and mild cathartic.

It is from the milky juice of the root that we obtain the officinal Scammony, which is procured in the following manner by the peasants, who collect it in the beginning of June: "Having cleared away the earth from about the root, they cut off the top, in an oblique direction, about two inches below where the stalks spring from it. Under the most depending part of the slope they fix a shell, or some other convenient receptacle, into which the milky juice gradually flows. It is left there about twelve hours, which time is sufficient for draining off the whole juice: this, however, is in small quantity, each root affording but a very few drachms. This juice from the several roots is put together, often into the leg of an old boot, for want of some more proper vessel, where in a little time it grows hard, and is the genuine Scammony." This concrete is a gummy-resin, generally of a light, shining, grey colour, and friable texture. It is brought from Aleppo and Smyrna; that which comes from the latter place is less valued than the former, and is supposed to be more ponderous and of a deeper colour; but the colour affords no test of the goodness of this drug, which seems to depend entirely upon the purity of the concrete. The smell of Scammony is rather unpleasant, and the taste bitterish and slightly acrid. The different proportions of gum and resin of which it consists, have been variously stated, but as proof spirit is the best menstruum for it, these substances are supposed to be nearly in equal parts.

Scammony appears to have been well known to the Greek and Arabian physicians, and was not only employed internally as a purgative, but also as an external remedy for tumours, scabies, tinea,

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fixed pains, &c. Although this drug was seldom given alone, yet we find it was very generally used, and an ingredient in many compounds which were formerly held in very great repute. Hoffman, however, entertained an opinion, that Scammony was a dangerous medicine; Ego nunquam in praxi mea in usu habui, nec in posterum habebo; me semper ab istiusmodi venenis colliquativis abstinens." Hoff. in Schrod. p. 543. But since Boerhaave's time it has been considered as a safe though stimulating cathartic, and frequently prescribed uncombined with any other substance, yet neither producing tormina nor hypercatharsis. Like other resinous purgatives it is uncertain in its operation, which may be occasioned by the intestines being more or less defended from the action of these stimulants, by the quantity of natural mucus with which they are covered.

2. C. Jalapa. Jalap Bindweed. The root is perennial, large, ponderous, abounding with a milky juice, of an irregular oval form, and blackish colour; the stalks are numerous, shrubby, slender, twisted, striated, rising above ten feet high, and twining for support round the neighbouring plants; the leaves are various, generally more or less heart-shaped, but often angular, or oblong and pointed; they are smooth, of a bright green colour, and stand alternately upon long footstalks; the flowers are produced from short branches, sending off two peduncles, each of which supports a single flower; this is large, bell-shaped, entire, plicated, externally of a reddish colour, but of a dark purple within; the calyx consists of five oval leaves; these are concave, somewhat indented at their points, and of a pale green colour; the filaments are five, slender, short, and the antheræ large, and yellow; the style is shorter than the stamina; the stigma is round, and the germen oval. It is a native of South America, and flowers in August and September. The plant was introduced into the royal garden at Kew in 1778, by Monsieur Thouin; and under the direction of Mr. Aiton it acquired great vigour and luxuriance, extending its stalks fifteen feet in length; and, by means of slips obtained from it, two healthy young plants have since been produced: this circumstance is the more fortunate, as the parent plant lately died. Botanists have differed much respecting the officinal Jalap plant; Linnæus following Clusius, Plumier, Tournefort, and others, first referred it to the Mirabilis, but in the second edition of his Materia Medica

he adopts the opinions of Ray and Miller, in considering it a Convolvulus; and indeed after the account of this plant given by Dr. Houston, we are surprised that any doubt should still remain upon this subject.

It is said that the root of Jalap was first brought to Europe about the year 1610, and took its name from Xalapa, a province or town in New Spain. In the shops we find this root both cut into slices, and whole, of an oval shape, solid, ponderous, blackish on the outside, but grey within, and marked with several dark veins, by the number of which, and by its hardness, heaviness, and dark colour, the goodness of the root is to be estimated. It has scarcely any smell, and very little taste, but to the tongue and to the throat manifests a slight degree of pungency. The medicinal activity of Jalap resides principally, if not wholly, in the resin, which though given in small doses, occasions violent tormina. The gummy part bears an inconsiderable proportion to the resinous, and is found to have little or no cathartic power, but as a diuretic it is extremely active. That Jalap is an efficacious and safe purgative daily experience must evince, but according as the root contains more or less resin, its effects must of course vary. Hoffman thought it particularly improper and unsafe to administer this medicine to children: but Dr. Cullen observes, that if Jalap" be well triturated before exhibition with a hard powder, and the crystals of tartar are the fittest for the purpose, it will operate in lesser doses than when taken by itself, and at the same time very moderately and without griping." [Linn. Ray. North. Woodville.

SECTION XX.

Aloes Tree.

Aloe Spicata.-SIBTHORP.

SEVEN species belong to this genus, some of them yielding a warm, purgative gum. The root of the species before us is perennial, strong, fibrous: the flower-stems rise three or four feet in height, and are smooth, erect, of a glaucous green colour, and towards the top beset with ovate bracteal scales: the leaves are numerous, and proceed from the upper part of the root: they are narrow, tapering, thick, or fleshy, succulent, smooth, glaucous, and

beset at the edges with spiny teeth: the flowers are produced in terminal spikes, and of a purple or reddish colour: there is no calyx : the corolla is monopetalous, tubular, nectariferous, cut into six narrow leaves, which separate at the mouth: the filaments are six, tapering, yellowish, inserted into the receptacle, and furnished with oblong orange-coloured anthers: the germen is oblong, supporting a simple slender style, of the length of the filaments, and terminated by an obtuse stigma: the capsule is oblong and divided into three cells, with as many valves, and contains many angular seeds.

It is a native of Africa, and flowers most part of the year.

Not only the succotrine aloes, which is the inspissated juice of the plant here represented, but also the hepatic or Barbadoes aloes, is directed for officinal use in our pharmacopoeias. This however being obtained from another variety of the same species, viz. the aloe (a. vera) with thick denticulate spinous leaves, spotted on the surface, and shooting in every direction, we shall not particularly notice it. Besides, it appears probable from the observations of professor Murray, that different species as well as varieties of aloe would furnish the various kinds of this drug, and that Linnæus, by referring these sorts to those plants, the recent juice of which seemed to respectively correspond the nearest to them in taste, might easily be misled for Murray upon tasting the fresh juice of many different species of aloe, sometimes found it bitter, and at other times totally devoid of bitterness.

A tract of mountains about fifty miles from the Cape of Good Hope is wholly covered with the aloes plants, which renders the planting of them there unnecessary; but in Jamaica and Barbadoes they are now carefully cultivated; to the former of these islands, they were first brought from Bermuda, and gradually propagated themselves. They require two or three years standing before they yield their juice in perfection; to procure which, according to Dr. Browne, "The labourers go into the field with tubs and knives, and cut off the largest and most succulent leaves close to the stalk; these are immediately put into the tubs, and disposed one by the side of another in an upright position, that all the loose liquor may dribble out at the wound. When this is thought to be almost wholly discharged, the leaves are taken out one by one, passed through the hand, to clear off any part of the juice that may yet adhere, or stick

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in the less open veins; and the liquor put in shallow flat-bottomed vessels, and dried gradually in the sun, until it acquires a proper consistence. What is obtained in this manner is generally called succotrine aloes, and is the clearest and most transparent, as well as the highest in esteem and value." The method of procuring the common aloes he states to be nearly the same with that mentioned by Mr. Hughes, and lately by Mr. Millington: after a sufficient quantity of juice is drained from the leaves, to make it an object for the boiling-house, the last-mentioned gentleman informs us, "three boilers, either of iron or copper, are placed to one fire, though some have but two, and the small planters only one. The boilers are filled with juice, and as it ripens or becomes more inspissated, by a constant but regular fire, it is ladled forward from boiler to boiler, and fresh juice is added to that farthest from the fire, till the juice in that nearest to the fire (by much the smallest of the three, and commonly called by the name of tatch, as in the manufactory of sugar) becomes of a proper consistency to be skipped or ladled out into gourds, or other small vessels, used for its final reception. The proper time to skip or ladle it out of the tatch, is when it is arrived at what is termed a resin height, or when it cuts freely, or in thin flakes from the edges of a small wooden slice, that is dipped from time to time into the tatch for that purpose. A little lime-water is used by some aloe boilers during the process, when the ebullition is too great." He adds, "as to the sundried aloes which is most approved for medicinal purposes, very little is made in Barbadoes. The process is however very simple, though extremely tedious. The raw juice is either put into bladders, left quite open at top, and suspended in the sun, or in broad shallow trays of wood, pewter, or tin, exposed also to the sun every dry day, until all the fluid parts are exhaled, and a perfect resin formed, which is then packed up for use, or for exportation."

These accounts of procuring the aloes differ considerably from that given by Dr. Wright, who says, "Hepatic aloes is obtained in the following manner. The plant is pulled up by the roots and carefully cleansed from earth or other impurities. It is then sliced and cut in pieces into small hand-baskets or nets. These nets or baskets are put into large iron boilers with water, and boiled for ten minutes, when they are taken out, and fresh parcels supplied till the

VOL. V.

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