Cellular Energy Metabolism and Its RegulationCellular Energy Metabolism and Its Regulation examines the metabolic and molecular aspects of living organisms. Beginning with a discussion of evolutionary design and its close analogy with human design, it emphasizes the notion that evolution is a process of functional design, and that the characteristics of an organism, whether morphological or molecular, were selected because of functional advantage to the organism's ancestors. Thus, the study of an enzyme, a reaction, or a sequence can be biologically relevant only if its position in the hierarchy of function is kept in mind. This book dea ... |
Contents
Evolutionary Design | 1 |
Enzymes as Control Elements | 5 |
Conservation of Solvent Capacity and of Energy | 20 |
Copyright | |
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acetyl-SCOA AcSCOA activity adenine nucleotides adenylate energy charge adenylate kinase adenylate pool affinity AGš amino acids amount ATP equivalents ATP/ADP biosynthetic branchpoint carbon catalyzed cell Chapter chemical complex compounds concentration of ATP concentration of substrate concentration ratio conversion cost coupling agents coupling coefficient curve decrease diphosphate discussed dissociation effect electrons energy charge energy charge values entropy enzyme catalyzing equation equilibrium constant flux free energy free energy change fructose function glucose glycogen glycolysis growth H₂O hexose Hill plot hydrolysis illustrated increase interactions intermediates kcal/mole kinetic control ligand metabolic sequences metabolites Michaelis constant modifier mole fraction molecule moles of ATP NADH NADP+ NADPH organism overall oxaloacetate oxidation parameter pathway pentose phosphate phosphoenolpyruvate phosphofructokinase physiological protein pyruvate reactants reaction catalyzed reaction velocity regulation regulatory enzymes relative response shown in Figure slope stoichiometric storage substrate substrate concentration subunits synthesis temperature thermodynamic tion vivo