Fetal and Neonatal Brain Injury: Mechanisms, Management and the Risks of PracticeDavid K. Stevenson, Philip Sunshine, William E. Benitz Now in its third edition, this is a comprehensive survey of fetal and neonatal brain injury arising from hypoxia, ischemia or other causes. The volume spans a broad range of areas from epidemiology and pathogenesis, through to clinical manifestations and obstetric care, and then on to diagnosis, long-term outcomes, and medico-legal aspects. An important theme running throughout is to highlight scientific and clinical advances that have a role to play in minimising risk, improving clinical care and outcomes. |
Contents
Perinatal asphyxia an overview | 3 |
Mechanisms of brain damage in animal models of hypoxiaischemia in newborns | 30 |
Cellular and molecular biology of perinatal hypoxicischemic brain damage | 58 |
Fetal responses to asphyxia | 83 |
Congenital malformations of the brain | 111 |
Prematurity and complications of labor and delivery | 129 |
Intrauterine growth retardation restriction | 145 |
Hemorrhagic lesions of the central nervous system | 175 |
Placental pathology and the etiology of fetal and neonatal brain injury | 519 |
Correlations of clinical laboratory imaging and placental findings as to the timing of asphyxial events | 544 |
Specific Conditions Associated with Fetal and Neonatal Brain Injury | 555 |
Hypoglycemia in the neonate | 557 |
Hyperbilirubinemia and kernicterus | 575 |
Polycythemia | 582 |
Hydrops fetalis | 590 |
Acidosisalkalosis | 597 |
Pregnancy Labor and Delivery Complications Causing Brain Injury | 189 |
Maternal diseases that affect fetal development | 191 |
Antepartum evaluation of fetal wellbeing | 212 |
Intrapartum evaluation of the fetus | 226 |
Obstetrical conditions and practices that affect the fetus and newborn | 244 |
Section II | 256 |
Fetal and neonatal injury as a consequence of maternal substance abuse | 274 |
Chorioamnionitis and its possible relation to subsequent cerebral palsy | 303 |
Bacterial sepsis in the neonate | 314 |
Neonatal bacterial meningitis | 333 |
Neurologic sequelae of congenital perinatal infection | 355 |
Perinatal human immunodeficiency virus infection | 377 |
Inborn errors of metabolism with features of hypoxicischemic encephalopathy | 392 |
Diagnosis of the Infant with Asphyxia | 409 |
Clinical manifestations of hypoxicischemic encephalopathy | 411 |
The use of the EEG in assessing acute and chronic brain damage in the newborn | 425 |
Structural and functional imaging of hypoxicischemic injury HII in the fetal and neonatal brain | 446 |
Nearinfrared spectroscopy and imaging | 490 |
Meconium staining and the meconium aspiration syndrome | 616 |
Persistent pulmonary hypertension of the newborn | 640 |
Pediatric cardiac surgery relevance to fetal and neonatal brain injury | 667 |
Management of the Depressed or Neurologically Dysfunctional Neonate | 675 |
Neonatal resuscitation immediate management | 677 |
Extended management | 696 |
Neuroprotective mechanisms after hypoxicischemic injury | 719 |
Neonatal seizures an expression of fetal or neonatal brain disorders | 739 |
Improving performance reducing error and minimizing risk in the delivery room | 789 |
Nutritional support of the asphyxiated infant | 795 |
Assessing the Outcome of the Asphyxiated Infant | 819 |
Assessment of preterm infants neurobehavioral functioning reliability validity normative data and prediction to age two | 821 |
Longterm followup of term infants with perinatal asphyxia | 833 |
Appropriateness of intensive care application | 863 |
Medicolegal issues in perinatal brain injury | 877 |
| 891 | |
Common terms and phrases
abnormalities acid acidosis acute amniotic fluid Apgar scores apoptosis arterial asphyxia associated birth weight brain damage brain injury cardiac cause cell cerebral blood flow cerebral palsy cesarean section chorioamnionitis Clin clinical cocaine congenital correlation decreased delivery developmental diagnosis disease disorders drug ECMO effects evaluation fetal fetal heart rate fetus fetuses gestational age glucose glutamate hemorrhage hydrops hypertension hypoglycemia hypoxemia hypoxia hypoxia-ischemia imaging incidence increased infection intrapartum ischemia ischemic IUGR labor lesions levels malformations maternal meconium membrane meningitis metabolic monitoring MSAF necrosis neonatal neurodevelopmental neurologic neuronal newborn infants NIRS normal Obstet Gynecol occur outcome oxide oxygen patients Pediatr Pediatr Res perinatal perinatal asphyxia Perinatol periventricular piglets placental PPHN pregnancy premature prenatal preterm infants protein pulmonary pulmonary hypertension receptor reported respiratory result risk factors seizures sepsis sequelae severe studies syndrome term infants therapy tion tissue umbilical cord uterine utero vascular women
References to this book
Forensic Neuropsychology: Legal and Scientific Bases Hans O. Doerr,Albert S. Carlin No preview available - 1991 |