The Prefrontal Cortex: Its Structure, Function, and Pathology : Proceedings of the 16th International Summer School of Brain Research, Held at the Royal Tropical Institute and the Royal Netherlands Academy of Sciences Amsterdam, the Netherlands, from 28 August to 1 September 1989Harry B. M. Uylings Thanks to a resurgence of interest and a recent proliferation of research techniques, much new and illuminating data has emerged during the last decade relating to the prefrontal cortex, particularly in primates and rodents. In view of this progress, the 16th International Summer School of Brain Research was held in Amsterdam, The Netherlands from 28 August to 1 September 1989, devoted to the topic of The Prefrontal Cortex: Its Structure, Function and Pathology'. The edited proceedings, embodied in this 85th volume of Progress in Brain Research', fall into three sections - the first of which, following two introductory chapters, discusses the present knowledge of the organization of prefrontal cortical systems. In the second section, developmental and plasticity aspects in rodent and human cortex are considered, whilst the third section deals extensively with the functional aspects characteristic for the prefrontal cortex in primates, rats and rabbits. The last section reviews several topics on dysfunction of prefrontal cortex in rat and man, including a historical review on psychosurgery. |
Contents
Development and Plasticity in Prefrontal Cortex | 167 |
Functional Aspects of Prefrontal Cortex | 311 |
Pathology of Prefrontal Cortex | 499 |
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acid activity adult afferent agranular amygdala anatomical animals association auditory axons basal ganglia behavior Brain Res caudal cells cerebral cortex cholinergic cingulate cortex circuit cognitive Comp connections cortical areas cortical plate deficits delay dendritic differentiation dopamine dopaminergic dorsal dorsolateral effects efferent fetal fibers footshock forebrain frontal cortex frontal lobe function ganglioside Goldman-Rakic grafts Groenewegen human increase injection innervation input Kolb KostoviƩ lateral layer limbic medial prefrontal cortex mediodorsal nucleus memory mesocortical metabolism motor msec Neafsey neocortex neonatal Neurosci nucleus accumbens orbital organization Pandya parietal pathways pattern PFCm Physiol posterior postnatal Powell premotor primate projections pyramidal neurons rabbits Rakic receptors regions response retrograde rhesus monkey role rostral schizophrenia sensory somatosensory spatial specific stimulation stress striatal striatum studies subcortical subplate subplate zone substantia nigra task temporal terminals thalamic nucleus tical tion Uylings ventral tegmental area visual cortex